Interstitial Lung Disease in a Dental Technician Diagnosed Through an Integrated Multidisciplinary Approach
Main Article Content
Keywords
Interstitial Lung Disease, Occupational exposure, Dental technicians, Bronchoalveolar lavage, Scanning electron microscopy–energy dispersive X-ray spectroscopy
Abstract
Evidence from the literature indicates that workers in the dental care sector are routinely exposed to hazardous airborne agents, particularly mineral and metal dusts. This occupational risk is further amplified in settings with inadequate ventilation and insufficient use of personal protective equipment. We discuss the case of a dental technician with a significant history of occupational exposure who presented to our clinic with exertional dyspnea. High-resolution computed tomography revealed fibrosing nonspecific interstitial pneumonia associated with emphysema, and spirometry showed a severe reduction in carbon monoxide diffusion capacity. After a multidisciplinary evaluation, we performed bronchoscopy with bronchoalveolar lavage (BAL), which revealed an abundance of macrophages. Scanning electron microscopy with energy-dispersive spectrometry of the BAL detected silicon oxide, calcium, iron, and traces of metals typical of dental alloys (titanium, aluminum), as well as rare earth elements and toxic pollutants. These findings supported the diagnosis of interstitial lung disease due to long-term occupational exposure in dental laboratories, enabling a minimally invasive diagnostic approach. This strategy obviated the need for transbronchial biopsy, thereby avoiding a procedure associated with a high risk of pneumothorax in this patient.
References
2. Rownaq Ali ABM, Dathan Alharbi HS, Sahmi Al-Subaie BF, Khanam HK, Kausher H. Knowledge and awareness on pneumoconiosis among dental technicians and senior dental technology students in Saudi Arabia. Bioin-formation. 2022;18(10):968-73. Doi: 10.6026/97320630018968 PubMed PMID: 37693921.
3. Choudat D, Triem S, Weill B, et al. Respiratory symptoms, lung function, and pneumoconiosis among self em-ployed dental technicians. Occup Environ Med. 1993;50(5):443-9. Doi: 10.1136/oem.50.5.443
4. Seldén A, Sahle W, Johansson L, Sörenson S, Persson B. Three Cases of Dental Technician’s Pneumoconiosis Related to Cobalt-Chromium-Molybdenum Dust Exposure. Chest. 1996;109(3):837–42. Doi: 10.1378/chest.109.3.837
5. Zhang S, Xiong J, Ruan X, Ji C, Lu H. Global burden of pneumoconiosis from 1990 to 2021: a comprehensive analysis of incidence, mortality, and socio-demographic inequalities in 204 countries and territories. Front Public Health. 2025;13:1579851. Doi: 10.3389/fpubh.2025.1579851
6. Qi XM, Luo Y, Song MY, et al. Pneumoconiosis: current status and future prospects. Chin Med J (Engl). 2021;134(8):898–907. Doi: 10.1097/CM9.0000000000001461
7. Li Y, Cheng Z, Fan H, Hao C, Yao W. Epigenetic Changes and Functions in Pneumoconiosis. Oxid Med Cell Lon-gev. 2022;2022:2523066. Doi: 10.1155/2022/2523066 PubMed PMID: 35096264.
8. Li J, Yin P, Wang H, et al. The burden of pneumoconiosis in China: an analysis from the Global Burden of Dis-ease Study 2019. BMC Public Health. 2022;22(1):1114. Doi: 10.1186/s12889-022-13541-x PubMed PMID: 35659279.
9. Guarnieri G, Salasnich M, Lucernoni P, et al. Silicosis in finishing workers in quartz conglomerates processing. Med Lav. 2020;111(2):99-106. Doi: 10.23749/mdl.v111i2.9115
10. Kahraman H, Koksal N, Cinkara M, Ozkan F, Sucakli MH, Ekerbicer H. Pneumoconiosis in dental technicians: HRCT and pulmonary function findings. Occup Med (Chic Ill). 2014;64(6):442-7. Doi: 10.1093/occmed/kqu047
11. Di Lorenzo L, Inchingolo F, Pipoli A, et al. Mixed-dust pneumoconiosis in a dental technician: a multidiscipli-nary diagnosis case report. BMC Pulm Med. 2022;22(1):161. Doi: 10.1186/s12890-022-01948-6 PubMed PMID: 35477357.
12. De Vuyst P, Vande Weyer R, De Coster A, et al. Dental technician’s pneumoconiosis. A report of two cases. Am Rev Respir Dis. 1986;133(2):316-20. Doi: 10.1164/arrd.1986.133.2.316 PubMed PMID: 3946927.
13. Tiraboschi MM, Sala E, Ferroni M, et al. Early signs of pneumoconiosis in a dental technician in Italy: a case report. BMC Pulm Med. 2021;21(1):352. Doi: 10.1186/s12890-021-01721-1 PubMed PMID: 34743717.
